DRD5 (Dopamine receptor D5)
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The D5 subtype dopamine receptor (DRD5) stimulates adenyl cyclase and is expressed in the neurons of the limbic region of the brain. Polymorphisms in DRD5 have been highly associated with attention deficit hyperactivity disorder (ADHD). Humans have approximately 5 more copies of DRD5 than any other primate, but the significance of this change is not understood.
The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation., , J Cell Sci, 2011 May 15, Volume 124, Issue Pt 10, p.1726-38, (2011)
Diversity of human copy number variation and multicopy genes., , Science, 10/2010, Volume 330, Issue 6004, p.641-6, (2010)
Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR., , Genomics, 2010 Apr, Volume 95, Issue 4, p.203-9, (2010)
Lineage-specific gene duplication and loss in human and great ape evolution., , PLoS Biol, 07/2004, Volume 2, Issue 7, p.E207, (2004)