MBL1P (mannose-binding lectin (protein A) 1, pseudogene)
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Mannose-binding lectin 1 (MBL1) is a member of the collectin family and is involved in binding multiple types of microorganisms to activate the lectin-complimentary pathway of innate immunity. Most mammals, including rodents and primates have two MBL genes, 1 and 2, however MBL1 has become a pseudogene in the human lineage. Implications for this loss are not understood.
Divergence, demography and gene loss along the human lineage., , Philos Trans R Soc Lond B Biol Sci, 2010 Aug 27, Volume 365, Issue 1552, p.2451-7, (2010)
Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates., , Genome Biol, Volume 11, Issue 3, p.R26, (2010)
Molecular genetic analysis of porcine mannose-binding lectin genes, MBL1 and MBL2, and their association with complement activity., , Int J Immunogenet, 02/2007, Volume 34, Issue 1, p.55-63, (2007)
Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes., , Mamm Genome, 02/1995, Volume 6, Issue 2, p.103-10, (1995)