PAK2 (p21 activated kinase 2)
Certainty Style Key
Certainty styling is being phased out topic by topic.
Hover over keys for definitions:Human Uniqueness Compared to "Great Apes":
Likely Difference
Human Universality:
Individual Universal (All Individuals Everywhere)
MOCA Domain:
p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2) is a serine/threonine kinase that is a target for the GTP binding proteins CDC42 and RAC1. PAK2 likely plays a role in regulating apoptosis and may be involved in neurite outgrowth. PAK2 has more copies in the human genome than in any other primate.
References
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CHL1 cooperates with PAK1-3 to regulate morphological differentiation of embryonic cortical neurons., , Neuroscience, 01/2010, Volume 165, Issue 1, p.107-15, (2010)
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Lineage-specific gene duplication and loss in human and great ape evolution., , PLoS Biol, 07/2004, Volume 2, Issue 7, p.E207, (2004)
