|Parental Investment Theory||
The correlation between parental investment and mate choice where the greater the parental investment the more selective, and the lesser the investment the greater the access to more mates (Trivers, 1972).
|Parietal Lobe (Brain)||
One of the major lobes in the human brain, roughly located at the upper back in the skull (“crown”). It processes sensory information such as touch, taste, and temperature, spatial senses and navigation (proprioception), and language processing.
A bacterium, virus, or other microorganism that can cause disease.
The biological mechanism (or mechanisms) that leads to a disease state and can also refer to the origin and development of a disease, and whether it is acute, chronic, or recurrent.
The absolute ability of an infectious agent to cause disease or damage in a host.
|Host, Infectious (Disease)|
Disordered physiological processes associated with disease or injury.
|Peer Review (Academic Publishing)||
The professional critique by other scholars or scientists from the same field that normally takes place before scholarly or scientific papers are accepted for publication.
The ability to see, hear, or become aware of something through the senses.
Observable traits of an organism that result from interactions between genes and environment during development.
The system that combines meaningless speech sounds into meaningful words.
A branching diagram showing the evolutionary relationships among biological species, or other entities, based on their physical or genetic characteristics.
Historical relationships of species or loci.
A genus of single-celled organisms that are obligate parasites of vertebrates and insects. In humans, malaria is caused by multiple species of Plasmodium and transmitted by mosquitos (commonly female Anopheles mosquitos).
|Anopheles Mosquitos, Genus, Malaria, Parasite|
The adaptability of an organism to changes in its environment or differences between its various habitats.
A geological epoch from ~2.5 mya to 11.7 kya characterized by a period of repeated glaciations. The end of the Pleistocene corresponds with the end of the last glacial period and also with the end of the Paleolithic age used in archeology. Subdivisions:
A bacterium that infects the lungs and sometimes the blood stream.
The idea that some genes are more easily expressed because of their chromatin state.
Relating to a trait determined by two or more genes. Most traits of organisms are polygenic.
|Polymerase chain reaction (PCR)||
A method of copying a specified locus.
An allelic difference observed in more than 1% of the population studied.
|Allele Frequency, Derived Alleles, Fixed Alleles|
|POM121||A gene that encodes for transmembrane nucleoporin, a protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus.|
A defined group of similar individuals among whom interbreeding occurs.
|Demography, Gene Flow|
|Positron Emission Tomography (PET) Neuroimaging||
A functional imaging technique used to observe metabolic process in the body.
Alter mature protein.
|Posterior Parietal Cortex||
The portion of parietal neocortex that plays an important role in planned movements, spatial reasoning, and attention.
The period of time after a woman has ceased ovulating. This life-stage is unique to humans and not expressed in non-human primates.
A genetic disorder usually caused by deletion of part of chromosome 15 inherited from the father, causing imbalance in sex-specific imprinting. Results in behavioral problems, intellectual disability, and short stature.
A pregnancy associated disorder characterized by high blood pressure and large amounts of protein in urine, typically accelerating during the third trimester.
|Prefrontal Cortex (Brain)||
The cerebral cortex that covers the front part of the frontal lobe and is linked to complex cognitive behavior, personality, long and short-term memory, decision making, speech, language, and a person’s will to live.
|Cerebral Cortex (Brain), Frontal Lobe (Brain)|
|Preprint (Academic Publishing)||
A version of a scholarly or scientific paper that has not yet been formally peer reviewed. It is freely available before it is published as a finished product in a peer-reviewed scholarly or scientific journal, which often include costly paywalls. It is generally not good practice for news outlets to report on preprinted results because they have not been peer-reviewed.
|Peer Review (Academic Publishing)|
|Primary Somatosensory Cortex||
A region of the Neocortex that controls tactile representation from the parts of the body.
A group of mammals that include humans, apes, monkeys, and prosimians.
A person, especially a young one, endowed with exceptional qualities or abilities.
The open-ended ability to combine meaningful linguistic units into new higher order units of meaning: for example, roots, prefixes (e.g. anti-), and suffixes (e.g. -ish) into words, and words (or signs) into phrases and sentences (Kluender, 2020).
Unicellular organisms that lack a membrane- bound nucleus, mitochondria, or any other membrane-bound organelle. (see Eukaryotes)
Predictor of positive outcome under most conditions, whether risk is low or high.
Region of DNA that initiates transcription of a particular gene.
A group of primates that includes all living and extinct galagos, lemurs, lorises, and tarsiers. They are considered to have characteristics that are more “primitive” (ancestral) than those of monkeys, apes, and humans.
Moderator of risk or adversity associated with better outcomes particularly when risk or adversity is high.
One of the four classes of major biomolecules. Proteins are molecules encoded by DNA sequences and composed of amino acids connected by peptide bonds. These range in size from a few animo acids (short peptides) to large molecules (long polypeptides) comprised of hundreds of amino acids.
|Amino Acid, DNA|
An informal term for unicellular (single celled) eukaryotes, either free-living or parasitic.
A ribosomal subunit that is activated by intracellular cascades and therefore used as a marker for neuron activity. This subunit is physically attached to RNA molecules that are being translated into protein and therefore can also provide information about which genes are expressed in active neurons.
|Psychological Evolutionary Barrier||
The mental equivalent of a physiological evolutionary barrier (such as the difficulty of evolving from an aquatic existence to living on land). A hypothetical concept.
The study of mental disorders.
High blood pressure in the blood vessels that supply the lungs. Also affects the right side of the heart.
An evolutionary model in which pronounced change takes place in short bursts followed by periods of evolutionary continuity. Compare with Continuity.
|Continuity (aka Phyletic Gradualism)|
The term used to refer to an infant rodent (rat or mouse).
An infant transport behavior in which the mother uses her mouth to gently carry a pup by the back of the neck. Mothers do this if pups crawl out of the nest or if she has to move her pups to a new nest location. In the laboratory, this behavior can be used as an index of maternal motivation because it is a proactive, voluntary response to an infant.
A type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal neurons are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract.
A primary progenitor cell capable of generating neurons, astrocytes, and oligodendrocytes. Radial glia are defined by their position, morphology, and genetic phenotype. These cells are involved in establishing a temporary scaffold for cortical layer development.
|Basal Radial Glia, Basal Ganglia (Brain), Outer Radial Glia|
|Reading-Frame||A way of dividing the sequence of nucleotides in a nucleic acid (DNA or RNA) molecule into a set of consecutive, non-overlapping triplets called codons.||Codon, DNA|
|Reading-Frame Shift||A genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three.||Codon, DNA, Mutation, Reading-Frame|
A subconscious defense mechanism characterized by refusal to acknowledge (or rationalization of) unwanted or unpleasant facts, realities, thoughts, or feelings. Related Term: “Denialism.”
A molecule on the surface of host cells used by pathogens for attachment and/or invasion. Examples: angiotensin-converting-enzyme 2 (ACE2) used by SARS- CoV- 2; Sialic acid used by influenza A.
|Influenza, Pathogen, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2), Sialic Acids|
Exchanges between chromosomes that causes independent inheritance of alleles.
|Red Blood Cells (RBCs)||
The most common type of blood cell and the vertebrate’s principal means of oxygen delivery from lungs or gills to all tissues of the body. RBCs of most mammals do not contain a nucleus with chromosomes. RBCs are also called “erythrocytes.”
Rapid eye movement sleep, a phase of mammalian sleep characterized by random movement of eyes, low muscle tone, and vivid dreams.
Age at which an individual initiates their reproductive career, influences lifetime reproductive success.
An individual’s production of offspring per breeding event or lifetime (also includes the reproductive success of the offspring). Compare with Fitness (Darwninian).
|Reproductive Tract (Human Female)||
The external (labia, clitoris, and vaginal opening) and internal (clitoris, uterus, fallopian tubes, and ovaries) sex organs that function in reproduction.
A population that is chronically infested with the causative agent of a disease and can act as a source of further infection.
Capacity (potential or manifested) of a system to adapt successfully to challenges that threaten system function, survival, or development; positive adaptation in the context of significant adversity exposure.
Associated with the act of respiration or breathing.
|Rising Star Cave System||
A system of caves in the Malmani dolomites of South Africa (and a part of the Cradle of Humankind World Heritage Site) where fossils of a previously unknown, extinct species of hominin, Homo naledi, were first discovered in 2013.
Higher probability of a negative (undesired) outcome.
Indicator of risk for specified negative outcome in a population.
Ribonucleic Acid. A molecule essential in gene coding, decoding, regulation, and expression. Consists of sequences of the four nucleotide bases: Adenine, Uracil, Guanine, and Cytosine. Types of RNA include messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and other non-coding RNAs. Some viruses including Influenza A and Sars-Cov-2 have RNA genomes.
|Gene, Nucleotides, Virus|
|RNA Binding Proteins (RBP)||
Proteins that bind RNA
A virus that has RNA (ribonucleic acid) as its genetic material. This nucleic acid is usually single-stranded RNA (ssRNA) but may be double-stranded RNA (dsRNA).
|Nucleic Acids, RNA, Virus|
|Sahelanthropus tchadensis (Toumaï)||
An extinct archaic species of hominin dating close to the split between the chimpanzee-human split, ~7 mya. A probable ancestor to Orrorin tugenensis and may have walked bipedally.
A genus of rod-shaped Gram-negative bacteria of the family Enterobacteriaceae and is divided by serovar type as either “non-typhoidal” Salmonella or “typhoidal” Salmonella. Salmonella enter the body through ingestion, often through consumption of contaminated meat, eggs, milk, or other foods that have come into contact with animal fecal matter. Its niche is in the intestines.
|Genus, Gram-Negative and Gram-Positive Staining, Serovar, “Non-typhoidal” Salmonella, “Typhoidal” Salmonella|
A bacterium species of the genus Salmonella. Most cases of salmonellosis in humans is caused by S. enterica, often via infected cattle or poultry, including eggs. S. enterica can be divided in six subspecies and comprise over 2,000 serovars.
|Bacteria, Genus, Salmonellosis, Serovar, Species|
|Salmonella enterica typhi||
A serovar of Salmonella enterica whose reservoir is the human body. It is usually contracted by ingestion of food or water that is contaminated by the feces of those carrying the organism.
|Reservoir (Medicine), Salmonella enterica, Serovar|
An intestinal infection caused by Salmonella bacteria. Common symptoms include diarrhea, fever, abdominal cramps, and vomiting.
Discontinuous evolution marked by a sudden mutational change from one generation to the next, and may result in a single-step speciation event.
Members of various Khoisan-speaking indigenous hunter-gatherer groups that are the first nations of Southern Africa, and whose territories span Botswana, Namibia, Angola, Zambia, Zimbabwe, Lesotho and South Africa. mtDNA and Y chromosome studies show that the San carry some of the most divergent (oldest) human haplogroups.
An ecosystem featuring hot, seasonally dry conditions, and vegetation consisting of open-canopy woodland and grassland.
A transitory ecotone between the tropical moist broadleaf forests of Equatorial Africa and the drier savannas and open woodlands to the north and south of the forest belt. The forest-savanna mosaic consists of drier forests, often gallery forest, interspersed with savannas and open grasslands.
A person affected with a mental disability who exhibits exceptional skill or brilliance in some limited field.
is a loose term that refers to people who have a combination of significant cognitive difficulties, often stemming from autism, and profound skills.
Organisms that search for and feed on carrion, dead plant material, or refuse.
A mental disorder characterized by delusions, hallucinations, disorganized speech and behavior, and other symptoms that cause social or occupational dysfunction (DSM-V, 2013).
Allele frequency change over time caused by the different replication rate of specific alleles.
A specific bond formed between a mother and her offspring, which results in the mother exclusively caring for her own young and actively rejecting non-familiar young.
Conscious knowledge of one’s own character, feelings, motives, and desires.
The study of the logic and meaning of a word, phrase, sentence, or text.
The linear order of the building blocks, which encodes individual form and function.
Reading the order of nucleotides in DNA.
A form of play that uses inquiry and innovation for complex problem-solving.
A subdivision within a species bacteria or viruses, or among immune cells of different individuals grouped together based on cell surface antigens.
|Antigen, Bacteria, Virus|
|Severe Acute Respiratory Syndrome (SARS)||
A contagious and sometimes fatal respiratory illness caused by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV or SARS-CoV-1). SARS was first reported in China in November 2002 and was rapidly spread worldwide by international travelers. Symptoms first appear flu-like with a fever, chills, muscle aches, headache and sometimes diarrhea. This can progress to a dry cough and shortness of breath. A massive global response helped to contain the spread of the disease and no new cases of the original SARS have been reported since 2004.
|Severe Acute Respiratory Syndrome Coronavirus 1 (SARS- CoV or SARS-CoV-1)|
|Severe Acute Respiratory Syndrome Coronavirus 1 (SARS- CoV or SARS-CoV-1)||
A strain of coronavirus that causes Severe Acute Respiratory Syndrome (SARS). It is a single-stranded RNA virus that infects the epithelial cells within the lungs and can infect humans, bats, and palm civets.
|Coronavirus, RNA virus, Severe Acute Respiratory Syndrome (SARS)|
|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2)||
A novel strain of coronavirus closely related to SARS-CoV that causes coronavirus disease 2019 (COVID-19), which resulted in a pandemic. It is a naturally evolving virus that crossed to humans from another animal, mostly likely a bat. SARS CoV-2 is completely different from the family that includes influenza viruses though both can cause respiratory symptoms.
|Coronavirus, Coronavirus Disease 2019 (COVID-19), Influenza, Novel (Disease), Pandemic, Respiratory, Severe Acute Respiratory Syndrome Coronavirus 1 (SARS- CoV or SARS-CoV-1), Virus|
Sequencing cuts the genome into short chunks that are read and reassembled by a computer.
Acidic sugar molecules prominently found at the outermost fringes of the forest of sugar chains (glycans) that cover all vertebrate cells. The two most common sialic acids in mammals are N-acetylneuraminic acid (Neu5Ac) into N glycolylneuraminic acid (Neu5Gc). The human lineage ceased the ability to produce Neu5Gc over 2 million years ago causing human cells to be coated with an excess of Neu5Ac.
An enzyme that cleaves sialic acid, an abundant sugar that coats most vertebrate cells.
|Sickle Cell Anemia||
An inherited red blood cell (RBC) disorder and one of the group of disorders of Sickle Cell Disease. In Sickle Cell Anemia, RBCs assume a sickle, or crescent shape, and degrade prematurely, causing a lack of red blood cells (anemia) to perform gas exchange. Shortness of breath, fatigue, and delayed growth and development in children are common conditions.
|Red Blood Cells (RBCs), Sickle Cell Disease|
|Sickle Cell Disease||
A group of inherited red blood cell disorders caused by the production of hemoglobin S, a protein in red blood cells (RBCs) that causes RBCs to assume a sickle, or crescent, shape. Sickled red blood cells break down prematurely, which causes the group of disorders, including Sickle Cell Anemia (a lack of red blood cells causing shortness of breath, fatigue, and delayed growth and development in children), jaundice (yellowing of the eyes and skin due to rapid breakdown of red blood cells), clotting (sickled red blood cells, which are stiff and inflexible, get stuck in small blood vessels depriving tissues and organs of oxygen-rich blood and can lead to organ damage, especially in the lungs, kidneys, spleen, and brain), and pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). Repeated infections, and periodic episodes of pain are also common. The severity of symptoms varies from person to person.
|Clotting (Blood), Hemoglobin S, Infection, Jaundice, Proteins, Pulmonary Hypertension, Red Blood Cells (RBCs), Sickle Cell Anemia|
|Sickle Cell Trait||
In humans, a condition in which a person is heterozygous for codominant alleles of the hemoglobin subunit beta (HBB) gene and produces both normal hemoglobin proteins (hgb) and abnormal hemoglobin proteins (hemoglobin S, which causes red blood cells (RBCs) to assume a sickle, or crescent, shape). In environments where malaria is endemic, humans with Sickle Cell Trait have a selective advantage as it confers some resistance to malaria. Sickle cells prevent the malaria parasite from stealing actin (a protein that maintains the pliable internal skeleton of RBCs). Actin is used by the parasite to transport another protein, adhesin (produced by the parasite), to the cell surface. Adhesin causes the infected red blood cells to adhere to each other and to vessel walls, resulting in microvascular inflammation. A person with Sickle Cell Trait does not display the severe symptoms of Sickle Cell Disease.
|Actin, Allele, Endemic, Gene, Hemoglobin, Hemoglobin S, Hemoglobin Subunit Beta Gene (HBB), Inflammation, Malaria, Parasite, Proteins, Red Blood Cells (RBCs), Sickle Cell Disease|
No change to the phenotype.