CARTA Glossary

Displaying 801 - 900 of 1174 defined words
Word Definition Related Vocabulary
Oldupai Gorge (Olduvai)

A 48km ravine in the Great Rift Valley in Tanzania that was occupied by hominins such as Homo habilis (1.9 mya) and Zinjanthropus (Australopithecus) boisei (1.8 mya). Today, Oldupai Gorge is an important paleoanthropological site and has been under excavation since 1913, most famously by Mary and Louis Leakey. “Oldupai” is the Maasai word for “the place of the wild sisal.”

Olfactory bulb (brain)

A neural structure of the vertebrate forebrain involved in sense of smell.

Oligodendrocytes (Brain)

A type of neuroglia that supports and insulates axons in the central nervous system of some vertebrates.

Oligo‐anovulation

Infrequent (oligo-) or absent (anovulation) ovulation. It is a common cause of irregular menstrual cycles and infertility in women of reproductive age.

Omnivore

An organism that derives its energy and nutrient requirements from a diet of plant, animal, and fungal origin.

Ontogenetic phase

A specific stage or period within an organism’s developmental history, encompassing changes in its phenotype (physical characteristics) and behavior from fertilization to adulthood, influenced by genes, environment, and maternal effects.

Ontogeny

The origin and development of an organism (from fertilization of the egg to the organism’s mature form). Can also refer to the study of an organism’s lifespan.

Open chromatin

The state of chromatin when DNA is less tightly packed and accessible to transcription factors, RNA polymerase, and regulatory proteins, allowing for gene expression. Open chromatin is found in regions of the genome that are actively being transcribed or are ready to be transcribed in a cell-type specific pattern.

Operational sex ratio (OSR)

The ratio of fertile males to fertile females that are ready to mate.

Optimism Bias

An almost universally human cognitive bias that seems to cause individuals to believe that they are at less risk of experiencing a negative event and more likely to experience a positive outcome compared to other people.

Optogenetic

A biological technique that involves the use of light to control gene expression and cellular function in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels.

Organoid Cell/tissue culture in vitro that aims to mimic organ structure and function.
Orthologous genes

Genes that are found in different species that evolved from a common ancestral gene and typically retain the same function.

Osteoarthritis

A chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations.

Otomi

A minority ethnic group of central Mexico during the 16th century CE.

Out of Africa

The widely accepted theory in human evolution that modern humans originated in Africa and later migrated to other parts of the world, replacing or interbreeding with local archaic human populations, such as Neanderthals and Denisovans.

Outer Radial Glia

Found in the outer subventricular zone of the neocortex, outer radial glia preferentially express genes related to extracellular matrix formation, migration, and stemness.

Outer Subventricular Zone A uniquely structured germinal zone that generates the expanded primate supragranular layers.
Ovulation

The timepoint of the menstrual cycle involving the release of an egg from an ovary.

Owl monkey (genus Aotus)

A New World monkey species found in Central and South America. Owl monkeys are nocturnal and have large, round eyes adapted for seeing in low-light conditions, giving them an “owl-like” appearance. Owl monkeys are social animals that typically live in small family groups and form strong pair bonds. They primarily feed on fruits, insects, and small vertebrates. Also known as the “night monkey” and “mirikina.”

Oxytocin

A peptide hormone made by the hypothalamus and stored in the pituitary gland, from which it is released into the blood stream. Oxytocin has many physiological and behavioral functions. It is considered “the love hormone” due to its association with reproduction, social bonding, sexual behavior, childbirth, maternal bonding, and milk production. Oxytocin is also an anti-inflammatory and is associated with sociostasis and longevity.

Oxytocin receptor

A protein found on the surface of cells that binds to the hormone oxytocin, triggering various physiological responses. These receptors are primarily located in the uterus, mammary glands, brain, and other tissues involved in reproduction and social interactions. The activation of oxytocin receptors helps coordinate functions like labor, emotional bonding, and even responses to stress. The gene encoding the oxytocin receptor is called OXTR.

Pair bond

The formation of long-lasting bonds between two individuals.

Paired receptors

Related membrane proteins that have similar extracellular appearance but opposite signaling functions and are found in pairs or clusters primarily on immune cells.

Paleolithic

A broad prehistoric period during which stone was used to make tools and weapons and is synonymous with Stone Age. During the paleolithic, hunting and gathering (foraging) was the primary subsistence method. The period ended with a flourishing of culture, not only in the manufacture of new stone (and bone tools) and other innovations (such spear thrower, bow and arrow, eyed needle, fishing implements), but also the development of splendid cave art paintings and engravings. Subdivisions:

  • Lower Paleolithic: ~3.4 million years ago (mya) - 300 thousand years ago (kya).
  • Middle Paleolithic: Consists of use of prepared cores (i.e. Levallois Technique) and hafted tools and weapons. ~300 - 30 kya.
  • Upper Paleolithic: Coincides with behavioral modernity and predates the advent of agriculture. Artifacts include finely crafted stone blades and bone and antler tools, such as harpoons and needles. ~50 - 10 kya.
Pandemic

An epidemic that has spread across regions, including multiple continents or worldwide.

Parallel architecture

A theory of the mental representations (or “data structures”) involved in the language faculty that are organized by phonology, syntax, and semantics.

Paranthropus

A genus of extinct bipedal hominins dating to ~ 2.6 mya to 1.1 mya that lived throughout eastern and south Africa. Their robust cranialdental anatomy suggests an adaptation to a diet of tough vegetation. Possible tool use is indicated by hands adapted for precision grasping. They probably descended from the gracile australopithecine hominids (Australopithecus) ~2.7 million years ago, hence their alternative name, robust australopithecine, and ongoing debate on genus.

Parasite

An organism that lives on or in a host organism at the expense of the host.

Parasitism

A close relationship between two organisms where one benefits at the expense of the other.

Parental Behavior

Any behavior of a member of a species toward an immature conspecific that increases the likelihood that the immature organism will survive to maturity.

Parental conflict

Evolutionary conflict between the sexes arising from differences in optimal parental investment in offspring across a lifetime.

Parental effort

The portion of reproductive effort in form of parenting (protection, feeding, provisioning).

Parental Investment

The investment of resources (time, energy, provisions) into offspring.

Parental Investment Theory

The correlation between parental investment and mate choice where the greater the parental investment the more selective, and the lesser the investment the greater the access to more mates (Trivers, 1972).

Parietal lobes

A pair of regions located at the top-back of each hemisphere of the brain that receives and interprets sensory information and help coordinate spatial orientation, and contribute to attention and perception.

Parieto-occipital association cortices (brain)

High-order cortical regions located at the junction of the parietal and occipital lobes that integrate multisensory information, particularly relating to spatial awareness, visual attention, and navigation.

Pastoralist

A person or group whose livelihood is based primarily on the domestication and herding of livestock rather than on farming crops.

Paternal investment

The parental effort of fathers.

Paternity

The state of being a father or the biological relationship between a father and his offspring.

Paternity assessment

The ability of males to assess the likelihood of having sired a particular offspring.

Paternity confidence

A male’s confidence in being the father of one or more offspring. Synonymous with father uncertainty.

Paternity uncertainty

Uncertainty about paternity due to female mating behavior.

Pathogen

A bacterium, virus, or other microorganism that can cause disease.

Pathogenesis

The biological mechanism (or mechanisms) that leads to a disease state and can also refer to the origin and development of a disease, and whether it is acute, chronic, or recurrent.

Pathogenicity

The absolute ability of an infectious agent to cause disease or damage in a host.

Pathophysiology

Disordered physiological processes associated with disease or injury.

Peer Review (Academic Publishing)

The professional critique by other scholars or scientists from the same field that normally takes place before scholarly or scientific papers are accepted for publication.

Penile Implants

Foreign objects embedded beneath the skin of the penis.

Peptide

A short chain of amino acids linked by peptide bonds. A peptide is a short protein.

Peptide bond

A covalent chemical bond that forms between two amino acids, linking them together in a peptide or protein chain. It occurs when the carboxyl group (-COOH) of one amino acid reacts with the amino group (-NH2) of another amino acid, releasing a molecule of water (a process called dehydration or condensation).

Perciption

The ability to see, hear, or become aware of something through the senses.

Perineum The area around the anus and genitals.
Period synchronization (or menstrual synchrony)

The phenomenon whereby women appear to synchronize their menstrual cycles.

Periovulatory

Around the time of ovulation.

Peripartum depression

Depression that occurs during pregnancy.

Permanent body modification (PBM)

Intentional permanent or semipermanent alterations of the living human body for reasons such as ritual, folk medicine, aesthetics, or corporal punishment. In general, voluntary changes are considered to be modifications, and involuntary changes are considered mutilations.

Peyote (Lophophora williamsii)

A small, spineless cactus with psychoactive alkaloids (mescaline) that is native to Mexico and southwestern Texas.

Phenotype

Observable traits of an organism that result from interactions between genes and environment during development.

Phenotypic flexibility

The range of an individual’s reversible variation in behavior, morphology, physiology, and life-history traits in response to changes in their environment.

Pheromones

Molecules that are produced by one individual and have signal value for another individual of the same species.

Phonology (Linguistics)

The organization of the sounds or signs in language.

Phosphorylation

A biochemical process in which a phosphate group (PO4 ³-) is added to a molecule, typically a protein, by an enzyme called a kinase. This addition of a phosphate group often occurs at specific amino acids in the protein, such as serine, threonine, or tyrosine, and it can significantly change the protein’s structure, function, or activity. Phosphorylation is a crucial mechanism of cellular regulation and plays a key role in controlling various cellular processes and also histone modification.

Phylogenetic Tree

A branching diagram showing the evolutionary relationships among biological species, or other entities, based on their physical or genetic characteristics.

Phylogeny

Historical relationships of species or loci.

Physiological trade-off

A compromise between different physiological needs of body functions.

Phytanic Acid

A branched chain fatty acid produced during the digestion of chlorophyll, especially in foregut fermenting species (ruminants) that consume plant materials. Humans obtain phytanic acid by consuming dairy products, ruminant animals, and some fish.

Phytanic Acid Metabolism (in humans)

Eating ruminants (red meat and dairy) creates special demands on detoxifying metabolism as phytanic acid (lipids) from plants eaten by ruminants can be toxic to humans.

Piercing

1. The deliberate creation of a hole in the skin and/or flesh, often to hold an ornament such as an earring. 2. perforation itself. (e.g., “I changed the jewelry in my piercing”). 4. The ornament that is worn in a perforation of the tissue. More accurately described as piercing jewelry, body piercing jewelry, or body jewelry. (e.g., “My piercing fell out”).

Pioneer transcription factor

A type of transcription factor that can open and bind to chromatin. They control enhancer activation and are important in the recruitment of other transcription factors and in controlling DNA methylation.

Placenta

A flattened circular organ, primarily of fetal origin, in the uterus of pregnant eutherian mammals, nourishing and maintaining the fetus through the umbilical cord.

Placentation

The process of forming and developing the placenta, the organ that facilitates nutrient and gas exchange between the mother and developing fetus during pregnancy.

Plasmodium

A genus of single-celled organisms that are obligate parasites of vertebrates and insects. In humans, malaria is caused by multiple species of Plasmodium and transmitted by mosquitos (commonly female Anopheles mosquitos).

Plasticity (brain)

The ability of the brain to change and adapt to new information. These changes can involve the establishment of new synapses or new neurons in some regions.

Playa de los Muertos

A village in Honduras occupied from before 700 BCE to ca. 200 BCE. It also refers to the style of figurines produced and used there.

Pleistocene

A geological epoch from ~2.5 mya to 11.7 kya characterized by a period of repeated glaciations. The end of the Pleistocene corresponds with the end of the last glacial period and also with the end of the Paleolithic age used in archeology. Subdivisions:

  • Early (Lower) Pleistocene: ~2.58 mya - 781 kya.
  • Middle Pleistocene: Emergence of Homo sapiens. 781 - 126 kya.
  • Late (Upper) Pleistocene: 126 - 11.7 kya.
PM2.5

A fine particulate matter (particles or droplets less than 3 microns in width) air pollutant that causes haze, reduces air quality, and can cause short- and long-term negative health effects.

Pneumococcus

A bacterium that infects the lungs and sometimes the blood stream.

Poised Gene

The idea that some genes are more easily expressed because of their chromatin state.

Polyandry

A mating system where females regularly mate with multiple males.

Polycystic ovaries

Ovaries that contain a large number of small, fluid-filled sacs called follicles, or cysts, just under the surface. These cysts are usually immature follicles that failed to develop properly during the menstrual cycle and did not release an egg (ovulate).

Polycystic Ovary Syndrome (PCOS)

A syndrome defined by the presence of two of three of the following criteria: oligo‐anovulation, hyperandrogenism and polycystic ovaries. It is the leading cause of anovulatory infertility and can be debilitating for some people with ovaries.

Polygenic

Relating to a trait determined by two or more genes. Most traits of organisms are polygenic.

Polygynandry

A mating system in which males and females mate with multiple partners.

Polygyny

A mating system where males regularly mate with multiple females.

Polymerase chain reaction (PCR)

A method of copying a specified locus.

Polymorphism

The “many forms,” or genetic variants, of a single gene that exist and are maintained in a population at a frequency of 1% or higher.

Polysaccharide

A large, complex carbohydrate made up of many monosaccharides (simple sugars) linked together by glycosidic bonds.

Polysialic acid

A homopolymer of sialic acids abundant in the brain and fish eggs and found on certain pathogenic bacteria.

POM121 A gene that encodes for transmembrane nucleoporin, a protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus.
Pontic-Caspian steppe

A vast grassland region in Eastern Europe and Western Asia, stretching from the northern shores of the Black Sea (Pontic) to the Caspian Sea. It forms the western part of the Eurasian Steppe and has played a crucial role in human migration, culture, and prehistoric population dynamics.

Population

A defined group of similar individuals among whom interbreeding occurs.

Population bottleneck

The dramatic reduction in population size, which often results in a loss of genetic diversity.

Positron Emission Tomography (PET) Neuroimaging

A functional imaging technique used to observe metabolic process in the body.

Post-partum amenorrhea (PA)

Temporary cessation of menstrual cycles after giving birth.

Post-translation Modifications

Alter mature protein.

Posterior Parietal Cortex

The portion of parietal neocortex that plays an important role in planned movements, spatial reasoning, and attention.

Posterior visual networks

Cortical networks, primarily in the occipital and posterior temporal/parietal lobes, that receive and integrate visual input from the eyes to support perception, recognition, and spatial awareness.

Postmenopausal Longevity

The period of time after a woman has ceased ovulating. This life-stage is unique to humans and not expressed in non-human primates.

Postpartum depression

Depression that occurs after pregnancy. 15% of women experience depression after childbirth, making this the most common complication of childbirth.

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